Our chemists are well experienced with asymmetric synthesis using either chemical or enzymatic transformations at mg to multi gram scale. The enantiomeric purity of each deliverable is adjudged through specific rotation as well as using chiral HPLC methods. In case of unknown substances, we perform synthesis in racemic series in parallel to avoid any ambiguity. Our expertise in this area is the following:
- Enantiospecific synthesis from chiral pool approach using commercially available amino acids, Terpenes and Carbohydrates
- Synthesis of compounds using chiral auxiliary approach
- Asymmetric catalysis for e.g. Sharpless’s Epoxidation, Dihydroxylation (AD)/Aminohydroxylation (AA) & Jacobsen’s hydrolytic kinetic resolution, and Reduction reactions (e.g. CBS catalyst and Noyori’s catalysis)
- Enzymatic acylation using immobilized Lipase
- Conventional resolution using acid/base approach
